Opening-up the stem cell niche: Hematopoietic stem cell transplantation without irradiation

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A novel mouse model allows for the transplantation of human blood-forming stem cells without the need for irradiation therapy. The results show that the Kit receptor is important for the function of human blood stem cells, notably in a transplantation setting. Further studies will now focus on using this knowledge about the role of the receptor to improve conditioning therapy in the …Opening-up the stem cell niche: Hematopoietic stem cell transplantation without irradiation

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